魏然
副教授，硕士研究生导师，博士
邮箱：wran@zafu.edu.cn
教育经历：
2014.9-2020.3 浙江大学 硕博连读（茶学博士）
2017.11-2019.10 University of California, Davis 国家公派联合培养博士
2010.9-2014.6 浙江农林大学 本科
研究方向：
（1）茶叶加工与品质化学
（2）茶功能性成分与深加工产品开发
承担课程：
主讲《茶学概论》《茶叶品质化学与分析》《植物饮料资源》《茶与健康》《茶文化专业英语》等相关课程。
主持重点基金课题：
2023 龙井茶加工过程中AGEs的产生规律及调控基础研究，国家自然科学基金青年项目
2023 四川特色茶植物资源功能因子研究及高值化利用，浙江省重点研发“尖兵、领雁”项目
2022 “香茶”数字化关键设备与中央集控设备研制与示范，浙江省“三农九方”科技协作项目
2021 遂昌香茶品质提升关键工艺研究，浙江省科技厅一般类项目
近5年部分学术成果（一作或通讯）：
1. Cake of Japonica, Indica and glutinous rice: Effect of matcha powder on the volatile profiles, nutritional properties and optimal production parameters, Food Chemistry-X, 2023.
2. Chlorogenic acid combined with epigallocatechin-3-gallate mitigates D-galactose-induced gut aging in mice, Food & Function, 2023.
3.Phospho-Aspirin (MDC-22) inhibits pancreatic cancer growth in patient-derived tumor xenografts and KPC mice by targeting EGFR: Enhanced efficacy in combination with irinotecan, Neoplasia, 2022.
4.Effects of Tea Powder on the Cooking Properties, Antioxidative Potential and Volatile Profiles of Dried Noodles, Foods, 2022.
5. (-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice, Food & Function, 2021.
6. EGCG sensitizes chemotherapeutic-induced cytotoxicity by targeting the ERK pathway in multiple cancer cell lines, Archives of Biochemistry and Biophysics, 2020.
7. Targeting glycolysis with Epigallocatechin-3-gallate enhances the efficacy of chemotherapeutics in pancreatic cancer cells and xenografts, Cancers, 2019.
8. Phospho-valproic acid (MDC-1112) reduces pancreatic cancer growth in patient-derived tumor xenografts and KPC mice: enhanced efficacy when combined with gemcitabine, Carcinogenesis, 2019.
9. Epigallocatechin-3-gallate (EGCG) suppresses pancreatic cancer cell growth, invasion, and migration partly through the inhibition of Akt pathway and epithelial–mesenchymal transition: enhanced efficacy when combined with gemcitabine, Nutrients, 2019.
10. Suppressing glucose metabolism with epigallocatechin-3-gallate (EGCG) reduces breast cancer cell growth in preclinical models, Food & Function, 2018.
